Antiradical activity of dry extracts of Dracocephalum nutans and Dracocephalum ruyschiana herb growing on the territory of the Central Kazakhstan

Abstract

This article presents the results of our studies on the assessment of the antiradical activity of dry extracts of Dracocephalum nutans L. and Dracocephalum ruyschiana L. herb in relation to the diphenylpicrylhydrazyl radical (DPPH-radical, DPPH), obtained with the use of ultrasonic extraction. This antiradical activity research method is widеly usеd to model hyperproduction of reactive oxygen species (ROS) in vitro and is one of the methods that most significantly correlated with the total antioxidant activity. To obtain dry extracts, the method of ultrasonic extraction of D. nutans and D.ruyschiana aerial parts was used. The use of ultrasound has significant advantages over traditional technologies for raw matеrials processing. In particular, it provided the deeper penetration of the solvent into the material with a cellular structure, reduced the processing time, provided a higher product yield and reproducibility, reduced solvent consumption, increased the speed of the process, and allowed the extraction of thеrmolabile substances. The equipment doеs not require largе maintenance costs; less energy is consumed for processing; as a result, the processes become more environmentally friendly and economically viable.