Reactions of tert-butyl phosphoramidites with carbon tetrachloride and chloroform

Abstract

The reactions of 2-tert-butoxy-3-phenyl-1,3,2-oxazaphospholane and di-tert-butyl diethylphosphoramidite with carbon tetrachloride and chloroform were studied. These reactions proceed via formation of an intermediate quasiphosphonium compound. In the process, carbon tetrachloride acts as a source of positively charged halogen, and chloroform, as a C-H acid.