Synthesis and Investigation of Biological Activity of New Betulonic Acid Derivatives Containing 1,2,3-Triazole Fragments

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dc.contributor.authorJalmakhanbetova, R.I.
dc.contributor.authorMukusheva, G.K.
dc.contributor.authorAbdugalimov, A.Sh.
dc.contributor.authorZhumagalieva, Zh.Zh.
dc.contributor.authorDehaen, W.
dc.contributor.authorAnthonissen, S.
dc.contributor.authorSuleimen, Y.M.
dc.contributor.authorSeidakhmetova, R.B.
dc.date.accessioned2025-01-24T10:41:02Z
dc.date.available2025-01-24T10:41:02Z
dc.date.issued2024
dc.description.abstractThe results of this study showed that the compounds synthesized by the authors have significant potential due to their antibacterial and cytotoxic properties. The apparent antibacterial activity demonstrated by the compounds suggests that they are active antimicrobial agents against common microbial pathogens that cause various socially significant infectious diseases. Compound 6 showed pronounced antimicrobial activity against the Gram-positive test strain Staphylococcus aureus ATCC 6538, and compound 7 demonstrated pronounced antimicrobial activity against the Gram-negative test strain Escherichia coli ATCC 25922 (MIC = 6.3 g/mL). This allowed us to consider these compounds to have greatru_RU
dc.identifier.citationSynthesis and Investigation of Biological Activity of New Betulonic Acid Derivatives Containing 1,2,3-Triazole Fragments/Jalmakhanbetova R.I.[et al.] // Molecules - 2024 - №29(3149) - pp. 1-21.ru_RU
dc.identifier.urihttps://rep.buketov.edu.kz//handle/data/19580
dc.language.isoenru_RU
dc.publisherMoleculesru_RU
dc.subjectbetulonic acidru_RU
dc.subjecttriterpenoidru_RU
dc.subjectlupaneru_RU
dc.subjectnatural productru_RU
dc.subjectchemical transformationru_RU
dc.subjectsynthesisru_RU
dc.subjectspectroscopic methodru_RU
dc.subjectcytotoxicityru_RU
dc.subjectantimicrobialru_RU
dc.titleSynthesis and Investigation of Biological Activity of New Betulonic Acid Derivatives Containing 1,2,3-Triazole Fragmentsru_RU
dc.typeArticleru_RU

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