The histochemical characteristic of pancreatic B-cells

Abstract

It is known that zinc possesses important role in processes of synthesis and formation of the deposited form of in pancreatic B-cells. Pancreas of many animals as of human contains a large amount of zinc. It is known also that some of chemicals and drugs capable to interact with zinc in B-cells that result destruction and death of cells. Authors have investigated the content of zinc in pancreatic islets of rabbit and features of localization in B-cells. It is established that the main amount of zinc concentrates in B-cells adjoining walls of blood ca- pillaries through which there is hormone exit in blood. Authors suppose that destruction of pancreatic islets past intravenous injection of diabetogenic chemicals result for the first of all — destruction of B-cells adjoining to blood capillaries in islets.