Synthesis and biological activity of nitrogen-containing derivatives of estafiatin
| dc.contributor.author | Merkhatuly, N. | |
| dc.contributor.author | Vojtíšek, P. | |
| dc.contributor.author | Abeuova, S.B. | |
| dc.contributor.author | Omarova, A.T. | |
| dc.contributor.author | Iskanderov, A.N. | |
| dc.date.accessioned | 2019-03-20T08:43:12Z | |
| dc.date.available | 2019-03-20T08:43:12Z | |
| dc.date.issued | 2014-06-30 | |
| dc.description.abstract | The reactions of guaianolide of estafiatin with various amines were investigated. It was shown that the aminolysis reactions of γ-lactone ring of estafiatin or reactions of Michael-type conjugate addition or tandem conversions of Michael and Knoevenagel-type were carried out depending on the nature of amines. The regularity of proceeding of estafiatin reactions with secondary aliphatic and aliphatic-aromatic amines was detected. It lies in the fact that the reactions proceed exclusively by Michael reaction and they are completely regioand stereoselective. It was revealed that synthetic nitrogen-containing derivatives of estafiatin had antibacterial and antioxidant activity. | ru_RU |
| dc.identifier.citation | Synthesis and biological activity of nitrogen-containing derivatives of estafiatin / N.Merkhatuly [et al.] // Қарағанды универисетінің хабаршысы. ХИМИЯ Сериясы.=Вестник Карагандинского университета. Серия ХИМИЯ.=Bulletin of the Karaganda University. CHEMISTRY Series. – 2014. - № 2. - P.4-8. | ru_RU |
| dc.identifier.issn | 0142-0843 | |
| dc.identifier.uri | https://rep.buketov.edu.kz:80//handle/data/4498 | |
| dc.language.iso | en | ru_RU |
| dc.publisher | KSU Publ. | ru_RU |
| dc.relation.ispartofseries | Қарағанды универисетінің хабаршысы. ХИМИЯ Сериясы.=Вестник Карагандинского университета. Серия ХИМИЯ.=Bulletin of the Karaganda University. CHEMISTRY Series.;№ 2(74)/ 2014 | |
| dc.subject | guaianolide | ru_RU |
| dc.subject | estafiatin | ru_RU |
| dc.subject | aminolysis | ru_RU |
| dc.subject | aliphatic amines | ru_RU |
| dc.subject | Michael reaction | ru_RU |
| dc.subject | tandem reaction | ru_RU |
| dc.subject | antibacterial and antioxidant activity | ru_RU |
| dc.title | Synthesis and biological activity of nitrogen-containing derivatives of estafiatin | ru_RU |
| dc.title.alternative | Эстафиатиннің азотқұрамды туындыларының синтезі жəне биологиялық белсенділігі | ru_RU |
| dc.title.alternative | Синтез и биологическая активность азотсодержащих производных эстафиатина | ru_RU |
| dc.type | Article | ru_RU |
| dcterms.type | Article |