Antiradical and Antimicrobial Activity of Thiosemicarbaside and 1,2,4-Triazole Derivatives of Hydroxybenzoic Acid

Simple item page
dc.contributor.authorSatpaeva, Zh.B.
dc.contributor.authorShulgau, Z.T.
dc.contributor.authorAkhmetova, S.B.
dc.contributor.authorNurkenov, O.A.
dc.contributor.authorFazylov, S.D.
dc.contributor.authorBurkeev, M.Zh.
dc.date.accessioned2022-04-11T04:32:58Z
dc.date.available2022-04-11T04:32:58Z
dc.date.issued2020
dc.description.abstractThe antimicrobial and antioxidant activity of synthesized biologically active compounds have been evaluated in comparison with the standard antioxidant, ascorbic acid. The antioxidant activity of the compounds has been studied by their ability to interact with the 2,2-diphenyl-1-picrylhydrazyl radical (DPPH ). The proposed test system has revealed the pronounced antiradical activity of 2-(2-hydroxybenzoyl)-Nphenylhydrazinecarbothioamide (1) (IC50(DPPH) = 15.5 μM) and 2-(4-hydroxybenzoyl)N-phenylhydrazinecarbothiamide (2) (IC50(DPPH) = 31.7 μM). A weak antibacterial activity of these compounds has been shown against gram-positive and gram-negative test strains.ru_RU
dc.identifier.citationAntiradical and Antimicrobial Activity of Thiosemicarbaside and 1,2,4-Triazole Derivatives of Hydroxybenzoic Acid/ Satpaeva Zh.B.[et al.] // Russian Journal of Bioorganic Chemistry. - Vol.46.- №.4. - P.537–541ru_RU
dc.identifier.issn1068-1620
dc.identifier.urihttps://rep.buketov.edu.kz//handle/data/12143
dc.language.isoenru_RU
dc.publisherRussian Journal of Bioorganic Chemistryru_RU
dc.relation.ispartofseriesRussian Journal of Bioorganic Chemistry;
dc.relation.ispartofseries;№46 (4)
dc.subjectantioxidantru_RU
dc.subjectantiradicalru_RU
dc.subjectantimicrobial activityru_RU
dc.subjectstrainru_RU
dc.subjectfree radicalru_RU
dc.subjectthiosemicarbazideru_RU
dc.subject1,2,4-triazoleru_RU
dc.subjectDPPHru_RU
dc.titleAntiradical and Antimicrobial Activity of Thiosemicarbaside and 1,2,4-Triazole Derivatives of Hydroxybenzoic Acidru_RU
dc.typeArticleru_RU

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
Antiradical and Antimicrobial.pdf
Size:
1018.44 KB
Format:
Adobe Portable Document Format
Description:
Download

License bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

2020