Physico-chemical properties of ZnO doped nanostructured hydroxyapatite

Abstract

The modification of synthetic biomaterials based on bioapatite by various additives becomes urgent, which would have an antibacterial and antiseptic effect, in order to reduce the risk of transformation of aseptic inflammation to bacterial (osteomyelitis). The solution of this issue can be the inclusion of trace metal ions, such as Zn, Ag and Mg hydroxyapatite (HAP), which present in the biological bone mineral. The addition of zinc ions improves its biological characteristics, since recent studies show its antibacterial properties. This work is devoted to the synthesis and complex study of bioadaptive material based on ZnO doped nanostructured hydroxyapatite, which has properties close to bone tissue. The paper presents new results on the preparation and investigation of a composite material of HAP powder with the addition of ZnO. The investigation was carried out by scanning electron microscopy with the possibility of energy-dispersive analysis, transmission electron microscopy with the possibility of mapping the elemental composition. The morphology and the phase state of the particles have been studied. The ratio of Ca/P corresponds to the generally accepted parameters. In the study, it was found that HAP molecules are embedded in the crystal structure of ZnO and form a chemical bond with the substitution of the Ca atom.