Histological Changes in Pancreatic Islets of Animals with Experimental Diabetes Caused by Xanthurenic Acid under Condition of Suppression of Its Endogenous Synthesis
| dc.contributor.author | Meyramov, G. G. | |
| dc.contributor.author | Kohnert, К.-D. | |
| dc.contributor.author | Kikimbaeva, A. A. | |
| dc.contributor.author | Аitkulov, A. M. | |
| dc.contributor.author | Кystaubaeva, Z. T. | |
| dc.contributor.author | Тykeshanova, G. M. | |
| dc.contributor.author | Dupont, O.-N. | |
| dc.contributor.author | Laryushina, E. M. | |
| dc.contributor.author | Меyramova, A. G. | |
| dc.contributor.author | Zhuzbaeva, G. O. | |
| dc.contributor.author | Коvalenko, O. L. | |
| dc.contributor.author | Shaybek, A. S. | |
| dc.date.accessioned | 2018-01-25T07:51:20Z | |
| dc.date.available | 2018-01-25T07:51:20Z | |
| dc.date.issued | 2015-09 | |
| dc.description.abstract | Long-term administration of pyridoxine to rats kept on a diabetogenic diet stimulating endogenous synthesis of xanthurenic acid resulted in minimal glycemia, less pronounced decrease in insulin content in β-cells, and more intensive excretion of xanthurenic acid with urine. Histological changes were observed in 23% pancreatic islets, whereas in rats not treated with pyridoxine, destruction and necrosis of 40-45% β-cells were found in 38% of studied islets. | ru_RU |
| dc.identifier.citation | Histological Changes in Pancreatic Islets of Animals with Experimental Diabetes Caused by Xanthurenic Acid under Condition of Suppression of Its Endogenous Synthesis/ G. G. Meyramov[a.o.]//Bulletin of Experimental Biology and Medicine.-2015.-№5(159).-pp 680–684 | ru_RU |
| dc.identifier.issn | 0007-4888 | |
| dc.identifier.uri | https://rep.buketov.edu.kz/handle/data/2122 | |
| dc.language.iso | en | ru_RU |
| dc.publisher | Springer US | ru_RU |
| dc.relation.ispartofseries | Bulletin of Experimental Biology and Medicine;№5(159) | |
| dc.subject | xanthurenic diabetes | ru_RU |
| dc.subject | β-cells | ru_RU |
| dc.subject | Zn2+ions | ru_RU |
| dc.subject | pyridoxine | ru_RU |
| dc.title | Histological Changes in Pancreatic Islets of Animals with Experimental Diabetes Caused by Xanthurenic Acid under Condition of Suppression of Its Endogenous Synthesis | ru_RU |
| dc.type | Article | ru_RU |