Effects of Rhodiola semenowii extract on hematological parameters in experimental hypothyreosis

Abstract

Thyroid pathology has a leading position in clinical endocrinology. Diseases of the thyroid gland in terms of prevalence are comparable with diabetes mellitus, and far ahead of other endocrine disorders. Current treatment approaches of hypothyroidism are rarely based on the pathogenesis, and are reduced to hormone replacement therapy. The purpose of this study is to determine the general hematological parameters after correction of experimental hypothyroidism with an extract of the root of the plant R. semenowii both alone and in combination with potassium iodide. As a result of the study, we found that in the experimental treatment of hypothyroidism, the extract of the root of R. semenowii B. with a predominant content of rhodioflavonoside has a pronounced therapeutic effect, expressed in the normalization of the level of pituitary and thyroid hormones. The obtained results indicate the absence of toxic and damaging effects such as activation and inhibition of hematopoiesis after enteral administration of the root extract of R. semenowii.