Synthesis and characterization of polymeric nanoparticles based on albumin

Abstract

The influence of different factors (pH of medium, nature and quantity of solvent, etc.) on physicochemical characteristics of polymeric albumin nanoparticles has been investigated in this article. Using optimal condi- tions which have been found out empty albumin nanoparticles with satisfactory physicochemical characteris- tics (particle diameter in the range of 50–100 nm, polydispersity 0.130–0.180 and ζ-potential –11,3–31,0 mV) have been obtained. Synthesized nanoparticles are promising as drug delivery systems.