Synthesis and Biological Activity of Hydrazones of o- and p-Hydroxybenzoic Acids. Spatial Structure of 5-Bromo-2-hydroxybenzylidene-4-hydroxybenzohydrazide

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dc.contributor.authorNurkenov, O. A.
dc.contributor.authorSatpaeva, Zh. B.
dc.contributor.authorSchepetkin, I. A.
dc.contributor.authorKhlebnikov, A. I.
dc.contributor.authorTurdybekov, K. M.
dc.contributor.authorSeilkhanov, T. M.
dc.contributor.authorFazylov, S. D.
dc.date.accessioned2018-02-27T07:31:31Z
dc.date.available2018-02-27T07:31:31Z
dc.date.issued2017-10
dc.description.abstractA series of hydrazones based on hydrazides of o- and p-hydroxybenzoic acids have been prepared. N-(5-Bromo-2-hydroxybenzylidene)-4-hydroxybenzohydrazide has been studied by X-ray diffraction analysis;its molecule forms hydrogen bond with a solvating ethanol molecule. Biological activity of the synthesizedhydrazones towards cathepsin Е and(or) elastase of human neutrophils has been determined.ru_RU
dc.identifier.citationSynthesis and Biological Activity of Hydrazones of o- and p-Hydroxybenzoic Acids. Spatial Structure of 5-Bromo-2-hydroxybenzylidene-4-hydroxybenzohydrazide/O. A. Nurkenov[a.o.]// Russian Journal of General Chemistry.-2017.-№10(87).- pp. 2299–2306ru_RU
dc.identifier.issn1070-3632
dc.identifier.urihttps://rep.buketov.edu.kz/handle/data/2346
dc.language.isoenru_RU
dc.publisherMAIK NAUKA/INTERPERIODICA/SPRINGER, 233 SPRING ST, NEW YORKru_RU
dc.relation.ispartofseriesRussian Journal of General Chemistry;№10(87)
dc.subjecthydrazoneru_RU
dc.subjecthydroxybenzoic acid hydrazideru_RU
dc.subjectcathepsin Еru_RU
dc.subjectneutrophil elastaseru_RU
dc.subjectmolecular dockingru_RU
dc.titleSynthesis and Biological Activity of Hydrazones of o- and p-Hydroxybenzoic Acids. Spatial Structure of 5-Bromo-2-hydroxybenzylidene-4-hydroxybenzohydrazideru_RU
dc.typeArticleru_RU

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