Methods of analysis of glycoluril and its derivatives

Abstract

The present work provides the literature data generalization concerning analysis of glycoluril, its derivatives and related compounds that allows obtaining information about the structure and properties of these compounds. Basic methods for analysis of glycoluril and substances on the basis thereof are considered, advantages and disadvantages of these methods are described. The generalized results of the methods of analysis of glycoluril and its derivatives show that the majority of carried studies are focused on the revealing of purity and identification of related impurities for compounds that found practical application (drugs, monomers and polymers on the basis thereof). Consistent trend to active search of new methods to analyze macrocyclic and supramolecular systems synthesized on the basis of glycoluril is observed. The aim of the present review is to take attention of chemists to the most advanced methods of analysis of glycoluril and its derivatives with reference to promotion of further research. The literature analysis will be useful for researchers dealing with designing of new molecules based on glycoluril with given properties where the methods of process control and analysis of target compounds has a decisive importance.